An Opsin Monomer Scrambles Phospholipids

Environmental transmission scrambles coexistence patterns of avian influenza viruses.

Despite the recent accumulation of theoretical and empirical studies on avian influenza viruses (AIVs), the interactions among the diverse pool of strains remain poorly understood. One potential reason is multiple transmission routes. In this paper, we explore the behavior of a two-strain mathematical model of AIV dynamics with lifelong immunity to understand how the combination of direct and e...

United States scrambles for secure, safe isotope supply.

Opsin vs opsin: new materials for biotechnological applications

The need of new diagnostic methods satisfying, as an early detection, a low invasive procedure and a cost-efficient value, is orienting the technological research toward the use of bio-integrated devices, in particular bio-sensors. The set of know-why necessary to achieve this goal is wide, from biochemistry to electronics and is summarized in an emerging branch of electronics, called proteotro...

Redesign of the monomer–monomer interface of Cre recombinase yields an obligate heterotetrameric complex

Cre recombinase catalyzes the cleavage and religation of DNA at loxP sites. The enzyme is a homotetramer in its functional state, and the symmetry of the protein complex enforces a pseudo-palindromic symmetry upon the loxP sequence. The Cre-lox system is a powerful tool for many researchers. However, broader application of the system is limited by the fixed sequence preferences of Cre, which ar...

Discovery of Oldest DNA Scrambles Human Origins Picture

Scientists reveal the surprising genetic identity of early human remains from roughly 400,000 years ago in Spain. The bones were first thought to belong to European Neanderthals, but analysis showed they are genetically closer to the Siberian Denisovans. Analysis of the bones challenges conventional thinking about the geographical spread of our ancient cousins, the early human species called Ne...